Cell Cytotoxicity is a critical quality attribute (CQA) for the biological activity of immune cell therapy products (e.g., NK cells, CAR-NK cells, Tm cells, CAR-T or TCR-T cells, etc.), and it is an important element of product quality research and quality control. Compared with cell cytotoxicity methods such as lactate dehydrogenase (LDH) assay, 51Cr release assay, luciferase reporter gene assay, RTCA assay, the detection of CFSE- and 7-AAD-labelled cell killing by flow cytometry is safer, more convenient, faster and more stable.
Specification of Cell Cytotoxicity Detection Kit, Cytotoxicity Assay Kit (Adherent Target Cells)
Application of Cell Cytotoxicity Assay Kit (Adherent Target Cells)
It is suitable for the evaluation of the killing function of immune cell products such as NK cells, CAR-NK cells, CAR-T cells, TCR-T cells, Tm cells, etc. on different tumour cell lines (adherent target cells).
CMC and quality research phase: In the early development phase of cell therapy products, the cytotoxic effect is evaluated and the process is optimised.
Release testing, stability and comparability studies phase: During the mid-term process lock phase of cell therapy products, a cell killing method for the product is established, and release testing and stability testing of the cell product are performe.
Data of Cell <font face="Calibri">C</font>ytotoxicity <font face="Calibri">K</font>it (Adherent Target Cells)<o:p></o:p>
FACS analysis of the killing rate of NK cells against CFSE-labeled A549 target cells:<o:p></o:p>
<o:p> </o:p>
FACS analysis of the killing rate of NK cells against CFSE-labeled target cells of different solid tumors cells:<o:p></o:p>
<o:p> </o:p>
<font face="Calibri">If you want to know more kinds of </font><font face="Calibri">approved cellular and gene therapy products</font><font face="Calibri">, please visit our website.</font><o:p></o:p>
<o:p> </o:p>
<font face="Calibri">
</font>
<font face="Calibri">We can also offer kinds of </font><font face="Calibri">nk cell cytotoxicity assay kit</font> <font face="Calibri">for sale. If you are interested, please leave us a message.</font>
<font face="Calibri">
</font><o:p></o:p>
Loading comments...