Tadalista 10 is recommended for problems related to male genital function. Tadalafil helps men get and keep an erection by increasing blood flow to the penis in combination with sexual stimulation. Read the Patient Information Leaflet, if your pharmacist has one, before taking tadalafil each time you receive a refill. If you have any questions, ask your doctor or pharmacist. A high-fat meal may delay the onset of the medication’s effects. Take it at least 30 to 60 minutes before having sex, and it lasts up to 36 hours. Just take it once a day, please. Do not chew or crush the medication before taking it; take it with water.